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Article

Comprehensive evaluation of imputation performance in African Americans.

Journal of human genetics - 1 Jul 2012

Chanda Pritam, Yuhki Naoya, Li Man, Bader Joel S, Hartz Alex, Boerwinkle Eric, Kao W H Linda, Arking Dan E

Abstract excerpt

Imputation of genome-wide single-nucleotide polymorphism (SNP) arrays to a larger known reference panel of SNPs has become a standard and an essential part of genome-wide association studies. However, little is known about the behavior of imputation in African Americans with respect to the different imputation algorithms, the reference population(s) and the reference SNP panels used. Genome-wide SNP data...

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PMID: 22648186
DOI: 10.1038/jhg.2012.43
PMCID: PMC3477509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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