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Article

Haplotype variation and genotype imputation in African populations.

Genetic epidemiology - 1 Dec 2011

Huang Lucy, Jakobsson Mattias, Pemberton Trevor J, Ibrahim Muntaser, Nyambo Thomas, Omar Sabah, Pritchard Jonathan K, Tishkoff Sarah A, Rosenberg Noah A

Abstract excerpt

Sub-Saharan Africa has been identified as the part of the world with the greatest human genetic diversity. This high level of diversity causes difficulties for genome-wide association (GWA) studies in African populations-for example, by reducing the accuracy of genotype imputation in African populations compared to non-African populations. Here, we investigate haplotype variation and imputation in Africa, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22125220
DOI: 10.1002/gepi.20626
PMCID: PMC3568705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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