Article
CD14 polymorphisms correlate with an augmented risk for celiac disease in Italian patients.
Genes and immunity - 1 Sept 2012
Catamo E, Segat L, Lenarduzzi S, Petix V, Morgutti M, Crovella S
Abstract excerpt
Celiac disease (CD) is a T-cell-mediated chronic inflammatory disease characterized by autoimmune, immunological and environmental components, where genetic factors in addition to the main known risk factors (gliadin and human leukocyte antigen (HLA)-DQ haplotypes) are supposed to be involved. CD14 is a multifunctional receptor involved in the bacterial lipopolysaccharides-dependent signal transduction. The CD14...
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