Article
Association of the IL-15 and IL-15Rα genes with celiac disease.
Cytokine - 1 Nov 2017
Escudero-Hernández Celia, Plaza-Izurieta Leticia, Garrote José A, Bilbao José Ramón, Arranz Eduardo
Abstract excerpt
Celiac disease is a chronic autoimmune condition triggered by dietary gluten in genetically predisposed individuals and the treatment is a strict gluten-free diet. The major predisposing genes are HLA-DQA1 and HLA-DQB1, but these are not sufficient for disease development. One of the candidate genes worth studying is interleukin (IL)-15 gene, together with its specific receptor, IL-15Rα, as they participate in...
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