Article
A polymorphism in the CD14 gene is associated with Crohn disease.
Scandinavian journal of gastroenterology - 1 Feb 2002
Klein W, Tromm A, Griga T, Fricke H, Folwaczny C, Hocke M, Eitner K, Marx M, Duerig N, Epplen J T
Abstract excerpt
BACKGROUND: Inflammatory bowel diseases (IBD) are multifactorial disorders, characterized by failure to limit the inflammatory response to luminal antigens. Although genetic factors play an important role in the pathogenesis, little is known about the genes accountable. Immune response to intestinal bacteria seems to be crucial in the pathogenesis of IBD. METHODS: To evaluate the role of the CD14 gene in IBD, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
