Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High expression of p300 is linked to aggressive features and poor prognosis of Nasopharyngeal Carcinoma

30 May 2012

Abstract excerpt

BACKGROUND: Increased expression of transcriptional coactivator p300 has been observed in a variety of human cancers. However, the expression status of p300 protein/mRNA in nasopharyngeal carcinoma (NPC) tissues and its clinicopathologic/prognostic implication are poorly understood. METHODS: In our study, mRNA and protein expression levels of p300 was explored by reverse transcription-polymerase chain reaction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Hippo pathway signaling and YAP/TAZ
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22647238
DOI: 10.1186/1479-5876-10-110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High expression of p300 is linked to aggressive features and poor prognosis of Nasopharyngeal CarcinomaPMID 22647238Read ↗

EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinomaSemantic proximity Read ↗

High p27 expression is associated with a better prognosis in East Asian non-small cell lung cancer patientsSemantic proximity Read ↗

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal CarcinomaSemantic proximity Read ↗

Dysregulation of the p300/CBP histone acetyltransferases in human cancer.Semantic proximity Read ↗

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.Semantic proximity Read ↗

Life and death of transcriptional co-activator p300Semantic proximity Read ↗

Nasopharyngeal carcinoma with non-squamous phenotype may be a variant of nasopharyngeal squamous cell carcinoma after inhibition of EGFR/PI3K/AKT/mTOR pathway.Semantic proximity Read ↗

Emerging roles of p300/CBP in autophagy and autophagy-related human disordersSemantic proximity Read ↗

Identification of differential proteins in nasopharyngeal carcinoma cells with p53 silence by proteome analysis.Semantic proximity Read ↗

[Effect of mutation in the p300 transcription coactivator on transcriptional response and cell proliferation of human carcinoma cell lines].Semantic proximity Read ↗

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinomaSemantic proximity Read ↗

Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.