Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma

1 Jan 2019

Abstract excerpt

E1A Binding Protein P300 (EP300) is one of the mutations of genes involved in histone modifications in esophageal squamous cell carcinoma (ESCC). However, its clinical relevance, potential function and mechanisms have remained elusive. Methods: Genomic sequencing datas from 325 esophageal squamous cell carcinoma (ESCC) cases were integrated and screened a series of frequently mutated histone modifier genes. EP300...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related gene regulation
Share to Esophageal Cancer Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31632486
DOI: 10.7150/jca.34261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinomaPMID 31632486Read ↗

EP300-mutated esophageal squamous cell carcinoma exhibits unique genetic features：an Experimental StudySemantic proximity Read ↗

Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy.Semantic proximity Read ↗

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinomaSemantic proximity Read ↗

Genetic landscape of esophageal squamous cell carcinoma.Semantic proximity Read ↗

TGF‐βRII / EP300 /SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinomaSemantic proximity Read ↗

Identification and functional significance of MicroRNAs in esophageal squamous cell carcinomaSemantic proximity Read ↗

E2F transcription factor 1 is involved in the phenotypic modulation of esophageal squamous cell carcinoma cells via microRNA-375.Semantic proximity Read ↗

A combined approach on the impact of EP300 overexpression on drug resistance, invasion and stemness in breast cancerSemantic proximity Read ↗

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.Semantic proximity Read ↗

Identification of genomic alterations in oesophageal squamous cell cancer.Semantic proximity Read ↗

Roles of oncogenes in esophageal squamous cell carcinoma and their therapeutic potentials.Semantic proximity Read ↗

Experimental analysis of bladder cancer-associated mutations in EP300 identifies EP300-R1627W as a driver mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.