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Article

Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy - 1 Aug 2012

Marvig Rasmus Lykke, Søndergaard Mette S R, Damkiær Søren, Høiby Niels, Johansen Helle Krogh, Molin Søren, Jelsbak Lars

Abstract excerpt

The emergence of antibiotic-resistant Pseudomonas aeruginosa is an important concern in the treatment of long-term airway infections in cystic fibrosis patients. In this study, we report the occurrence of azithromycin resistance among clinical P. aeruginosa DK2 isolates. We demonstrate that resistance is associated with specific mutations (A2058G, A2059G, and C2611T in Escherichia coli numbering) in domain V of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22644032
DOI: 10.1128/AAC.00630-12
PMCID: PMC3421623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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