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Article

Two new point mutations at A2062 associated with resistance to 16-membered macrolide antibiotics in mutant strains of Mycoplasma hominis.

Antimicrobial agents and chemotherapy - 1 Oct 2001

Furneri P M, Rappazzo G, Musumarra M P, Di Pietro P, Catania L S, Roccasalva L S

Abstract excerpt

We describe two mutants of Mycoplasma hominis PG-21 which show resistance to 16-membered macrolides but susceptibility to lincosamides, obtained by in vitro exposure to increasing doses of josamycin. The 23S rRNA gene showed that each had a mutation (A2062G and A2062T) corresponding to nucleotide 2062 in Escherichia coli, which was associated with the acquired phenotype.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Drug Resistance, Bacterial

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Share to RNA, Ribosomal, 23S

Share to Sequence Homology, Nucleic Acid

Source

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Identifiers

PMID: 11557502
DOI: 10.1128/AAC.45.10.2958-2960.2001
PMCID: PMC90764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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