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Article

Identification of mutations in 23S rRNA gene of clarithromycin-resistant Mycobacterium intracellulare.

Antimicrobial agents and chemotherapy - 1 Feb 1994

Meier A, Kirschner P, Springer B, Steingrube V A, Brown B A, Wallace R J, Böttger E C

Abstract excerpt

Clarithromycin is a potent macrolide that has been used for treating infections with nontuberculous mycobacteria. Pairs of susceptible and resistant Mycobacterium intracellulare strains were obtained from patients with chronic pulmonary M. intracellulare infections undergoing monotherapy with clarithromycin. Nucleotide sequence comparisons of the peptidyltransferase region in 23S rRNAs from parental and resistant...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8192472
DOI: 10.1128/AAC.38.2.381
PMCID: PMC284463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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