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Article

Identification of a mutation associated with erythromycin resistance in Bordetella pertussis: implications for surveillance of antimicrobial resistance.

Journal of clinical microbiology - 1 Mar 2003

Bartkus J M, Juni B A, Ehresmann K, Miller C A, Sanden G N, Cassiday P K, Saubolle M, Lee B, Long J, Harrison A R, Besser J M

Abstract excerpt

Erythromycin treatment failures and in vitro resistance of Bordetella pertussis have been reported on several occasions in the past few years, but the mechanism of resistance has not been described. One potential mechanism, genetic modification of the erythromycin-binding site on the 23S rRNA of the 50S ribosomal subunit, has been observed in other bacteria. To explore this possibility, we amplified the portion...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12624047
DOI: 10.1128/JCM.41.3.1167-1172.2003
PMCID: PMC150313

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Source receipt: pubmed, retrieved 7 Sept 2026.

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