Article
Region-specific differences in brain melanocortin receptors in rats of the lean phenotype.
Neuroreport - 11 Jul 2012
Shukla Charu, Britton Steven L, Koch Lauren G, Novak Colleen M
Abstract excerpt
The brain melanocortin (MC) system is one of numerous overlapping systems regulating energy balance; it consists of peptides including α-melanocyte-stimulating hormone that act through melanocortin receptors (MCRs). Mutations and polymorphisms in MC3R and MC4R have been identified as one of the most common genetic contributors to obesity in human studies. Brain MC3R and MC4R are known to modulate energy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
