Article
Biased signaling at neural melanocortin receptors in regulation of energy homeostasis.
Biochimica et biophysica acta. Molecular basis of disease - 1 Oct 2017
Yang Li-Kun, Tao Ya-Xiong
Abstract excerpt
The global prevalence of obesity highlights the importance of understanding on regulation of energy homeostasis. The central melanocortin system is an important intersection connecting the neural pathways controlling satiety and energy expenditure to regulate energy homeostasis by sensing and integrating the signals of external stimuli. In this system, neural melanocortin receptors (MCRs), melanocortin-3 and -4...
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