Article
Interleukin-6 (IL-6) -572C-->G promoter polymorphism is associated with type 2 diabetes risk in Koreans.
Clinical endocrinology - 1 Feb 2009
Koh Soo Jeong, Jang Yangsoo, Hyun Yae Jung, Park Ju Yeon, Song Young Duk, Shin Kyung-Kyun, Chae Jey Sook, Kim Byung-Keuk, Ordovas Jose M, Lee Jong Ho
Abstract excerpt
OBJECTIVE: Increased levels of inflammatory markers, such as interleukin-6 (IL-6), are associated with type 2 diabetes (T2DM). We investigated the association of IL-6 gene polymorphisms with T2DM and circulating levels of IL-6 in Koreans. SUBJECTS: A total of 1477 subjects with normal glucose tolerance and 476 T2DM patients were included. MEASUREMENTS: We examined IL-6 -174G-->C, -572C-->G, -597G-->A and...
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