Article
A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus.
Molecular genetics and metabolism - 1 Jun 2004
Stephens Jeffrey W, Hurel Steven J, Cooper Jacqueline A, Acharya Jayshree, Miller George J, Humphries Steve E
Abstract excerpt
Circulating levels of interleukin-6 (IL-6) are raised in insulin resistant states such as obesity, impaired glucose tolerance (IGT), and type 2 diabetes mellitus (T2DM). Growing evidence suggests that IL-6 is not only produced by fat cells but is also capable of inducing insulin resistance in the...
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