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Article

Role of mtDNA haplogroups in COPD susceptibility in a southwestern Han Chinese population.

Free radical biology & medicine - 1 Aug 2012

Zheng Shizhen, Wang Changzheng, Qian Guisheng, Wu Guoming, Guo Ruiling, Li Qi, Chen Yan, Li Jin, Li Haining, He Binfeng, Chen Huaping, Ji Fuyun

Abstract excerpt

The interplay of a complex genetic basis with the environmental factors of chronic obstructive pulmonary disease (COPD) may account for the differences in individual susceptibility to COPD. Mitochondrial DNA (mtDNA) contributes to an individual's ability to resist oxidation, an important determinant that affects COPD susceptibility. To investigate whether mtDNA haplogroups play important roles in COPD...

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Identifiers

PMID: 22634148
DOI: 10.1016/j.freeradbiomed.2012.05.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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