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Article

Genetic variations in detoxification enzymes and HIF-1α in Japanese patients with COPD.

The clinical respiratory journal - 1 Jan 2013

Putra Andika Chandra, Tanimoto Keiji, Arifin Marina, Antariksa Budhi, Hiyama Keiko

Abstract excerpt

INTRODUCTION: Genetic factors contribute as major determinants in the pathophysiological mechanisms of chronic obstructive pulmonary disease (COPD). Therefore, identification of candidate genes and various gene polymorphisms have improved our understanding of COPD. OBJECTIVES: Clarify the genes, including HIF1A, that contribute to the development of COPD. METHODS: We compared the genotype frequencies of 12...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21651746
DOI: 10.1111/j.1752-699X.2011.00255.x

Genes

EPHX1
GSTP1
GSTM1
GSTT1
HMOX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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