Article
Kupffer cell engraftment across the major histocompatibility barrier in mice: bone marrow origin, class II antigen expression, and antigen-presenting capacity.
Journal of pediatric gastroenterology and nutrition - 1 Nov 1990
Paradis K, Sharp H L, Vallera D A, Blazar B R
Abstract excerpt
The source of population renewal for Kupffer cells (KC), the major antigen-presenting cells of the liver, remains controversial. Using a well-described murine bone marrow transplantation (BMT) model in which the donor and recipient are disparate at the major histocompatibility complex (MHC), we h...
Topics
- Animals
- Antigen-Presenting Cells
- Bone Marrow Transplantation
- Genotype
- Histocompatibility Antigens Class II
- Kupffer Cells
- Male
- Mice
- Time Factors