Article
Proteome analysis of protein partners to nucleosomes containing canonical H2A or the variant histones H2A.Z or H2A.X.
Biological chemistry - 1 Jan 2012
Fujimoto Satoru, Seebart Corrine, Guastafierro Tiziana, Prenni Jessica, Caiafa Paola, Zlatanova Jordanka
Abstract excerpt
Although the existence of histone variants has been known for quite some time, only recently are we grasping the breadth and diversity of the cellular processes in which they are involved. Of particular interest are the two variants of histone H2A, H2A.Z and H2A.X because of their roles in regulation of gene expression and in DNA double-strand break repair, respectively. We hypothesize that nucleosomes containing...
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