Article
The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins.
Autophagy - 1 May 2012
Taillebourg Emmanuel, Gregoire Isabel, Viargues Perrine, Jacomin Anne-Claire, Thevenon Dominique, Faure Mathias, Fauvarque Marie-Odile
Abstract excerpt
Initially described as a nonspecific degradation process induced upon starvation, autophagy is now known also to be involved in the degradation of specific ubiquitinated substrates such as mitochondria, bacteria and aggregated proteins, ensuring crucial functions in cell physiology and immunity. We report here that the deubiquitinating enzyme USP36 controls selective autophagy activation in Drosophila and in...
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