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Article

USP8 inhibition regulates autophagy flux and controls Salmonella infection

21 Mar 2023

Abstract excerpt

Introduction Ubiquitination is an important protein modification that regulates various essential cellular processes, including the functions of innate immune cells. Deubiquitinases are enzymes responsible for removing ubiquitin modification from substrates, and the regulation of deubiquitinases in macrophages during infection with Salmonella Typhimurium and Yersinia enterocolitica remains unknown. Methods To...

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PMID: 37026055
DOI: 10.3389/fcimb.2023.1070271

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