Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy

22 May 2012

Abstract excerpt

BACKGROUND: Human female meiosis is particularly error prone, leading to the generation of aneuploidy, a problem which increases dramatically with advancing age. Despite being of great clinical importance, the genesis of oocyte aneuploidy remains poorly understood. Cumulus cells (CCs) surround oocytes in antral follicles and play a crucial role in regulating their maturation. During this investigation, we aimed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Prenatal Screening and Diagnostics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22617123
DOI: 10.1093/humrep/des170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidyPMID 22617123Read ↗

Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expressionSemantic proximity Read ↗

Identification of a novel gene set in human cumulus cells predictive of an oocyte's pregnancy potentialSemantic proximity Read ↗

PCOS and Role of Cumulus Gene Expression in Assessing Oocytes QualitySemantic proximity Read ↗

Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases.Semantic proximity Read ↗

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndromeSemantic proximity Read ↗

Copy Number Variants in Premature Ovarian Failure and Ovarian DysgenesisSemantic proximity Read ↗

Identification of candidate genes associated with mitotic-origin aneuploidy: a genome-wide association study.Semantic proximity Read ↗

Specific genes are selectively expressed between cumulus and granulosa cells from individual human pre-ovulatory folliclesSemantic proximity Read ↗

Chromosome Abnormalities in the Human OocyteSemantic proximity Read ↗

Genes involved in human premature ovarian failureSemantic proximity Read ↗

Human blastocysts of normal and abnormal karyotypes display distinct transcriptome profilesSemantic proximity Read ↗

Cumulus Cell Transcriptome Signatures as Predictive Biomarkers in ART: A Cross-Sectional Prospective Study of Molecular Determinants for Embryo Competence and Pregnancy OutcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.