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Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

4 Sept 2012

Abstract excerpt

STUDY QUESTION: Oocyte developmental competence is altered in patients with polycystic ovary syndrome (PCOS); is gene expression in cumulus cells (CCs) from mature metaphase II oocytes of patients with PCOS altered as well? SUMMARY ANSWER: Compared with CCs from non-PCOS patients, the gene expression profile of CCs isolated from mature oocytes of patients with PCOS present alterations that could explain the...

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PMID: 22951915
DOI: 10.1093/humrep/des325

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