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Article

Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases.

Human reproduction (Oxford, England) - 1 Aug 2016

Tšuiko O, Nõukas M, Žilina O, Hensen K, Tapanainen J S, Mägi R, Kals M, Kivistik P A, Haller-Kikkatalo K, Salumets A, Kurg A

Abstract excerpt

STUDY QUESTION: Can spontaneous premature ovarian failure (POF) patients derived from population-based biobanks reveal the association between copy number variations (CNVs) and POF? SUMMARY ANSWER: CNVs can hamper the functional capacity of ovaries by disrupting key genes and pathways essential for proper ovarian function. WHAT IS KNOWN ALREADY: POF is defined as the cessation of ovarian function before the age...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Ovarian Follicle

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Source

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Identifiers

PMID: 27301361
DOI: 10.1093/humrep/dew142
PMCID: PMC4974666

Genes

ARFGAP3
BNC1
FMN2
IAPP
SCARB1
TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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