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Specific genes are selectively expressed between cumulus and granulosa cells from individual human pre-ovulatory follicles

24 Aug 2012

Abstract excerpt

During folliculogenesis, the granulosa cells differentiate into two cell types: cumulus cells (CCs) and mural granulosa cells (MGCs). The objective of the study was to generate and compare the transcriptomes of MGCs and CCs from the pre-ovulatory follicle to characterize the detailed profile of the two cell populations shortly before ovulation. Twenty-one IVF/ICSI patients undergoing controlled ovarian...

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PMID: 22923488
DOI: 10.1093/molehr/gas035

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