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Article

Adrenergic alpha-1 pathway is associated with hypertension among Nigerians in a pathway-focused analysis.

PloS one - 1 Jan 2012

Reder Nicholas P, Tayo Bamidele O, Salako Babatunde, Ogunniyi Adesola, Adeyemo Adebowale, Rotimi Charles, Cooper Richard S

Abstract excerpt

BACKGROUND: The pathway-focused association approach offers a hypothesis driven alternative to the agnostic genome-wide association study. Here we apply the pathway-focused approach to an association study of hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in 1614 Nigerians with genome-wide data. METHODS AND RESULTS: Testing of 28 pathways with biological relevance to hypertension,...

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Share to Blood Pressure
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Adrenergic, alpha-1

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Source

Open in PubMed Open full text

Identifiers

PMID: 22615923
DOI: 10.1371/journal.pone.0037145
PMCID: PMC3353888

Genes

DBP
PNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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