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Article

Modification of DNA bases in mammalian chromatin by radiation-generated free radicals.

Biochemistry - 28 Aug 1990

Gajewski E, Rao G, Nackerdien Z, Dizdaroglu M

Abstract excerpt

Modification of DNA bases in mammalian chromatin in aqueous suspension by ionizing radiation generated free radicals was investigated. Argon, air, N2O, and N2O/O2 were used for saturation of the aqueous system in order to provide different radical environments. Radiation doses ranging from 20 to 200 Gy (J.kg-1) were used. Thirteen products resulting from radical interactions with pyrimidines and purines in...

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PMID: 2261442
DOI: 10.1021/bi00486a014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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