Article
Oxidative mechanisms in carcinogenesis.
British medical bulletin - 1 Jul 1993
Guyton K Z, Kensler T W
Abstract excerpt
Cancer in humans and animals is a multistep disease process. In this process, a single cell can develop from an otherwise normal tissue into a malignancy that can eventually destroy the organism. The complex series of cellular and molecular changes that occur through the development of cancers can be mediated by a diversity of endogenous and environmental stimuli. Active oxygen species and other free radicals...
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