Article
The complexity of DNA damage: relevance to biological consequences.
International journal of radiation biology - 1 Nov 1994
Ward J F
Abstract excerpt
Ionizing radiation causes both singly and multiply damaged sites in DNA when the range of radical migration is limited by the presence of hydroxyl radical scavengers (e.g. within cells). Multiply damaged sites are considered to be more biologically relevant because of the challenges they present to cellular repair mechanisms. These sites occur in the form of DNA double-strand breaks (dsb) but also as other...
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