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Article

Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2

19 Apr 2012

Abstract excerpt

The discovery of microRNA (miR) represents a novel paradigm in RNA-based regulation of gene expression and their dysregulation has become a hallmark of many a tumor. In virally associated cancers, the host-pathogen interaction could involve alteration in miR expression. Epstein-Barr virus (EBV)-encoded EBNA2 is indispensable for the capacity of the virus to transform B cells in vitro. Here, we studied how it...

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PMID: 22614176
DOI: 10.1038/leu.2012.108

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