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Article

Epstein-Barr virus-mediated dysregulation of human microRNA expression

15 Nov 2008

Abstract excerpt

MicroRNAs (miRNAs) are a large class of small (approximately 22 nt) noncoding RNAs that negatively regulate gene expression most often at the level of translation, and have been shown to be key regulators in a variety of processes including development, cell cycle and immunity. The Epstein-Barr virus (EBV) is an oncogenic herpes virus endemic in humans that encodes at least twenty-two of its own miRNAs. Cellular...

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PMID: 19001862
DOI: 10.4161/cc.7.22.7120

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