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Article

microRNA profiling in Epstein–Barr virus-associated B-cell lymphoma

8 Nov 2010

Abstract excerpt

The Epstein-Barr virus (EBV) is an oncogenic human Herpes virus found in ∼15% of diffuse large B-cell lymphoma (DLBCL). EBV encodes miRNAs and induces changes in the cellular miRNA profile of infected cells. MiRNAs are small, non-coding RNAs of ∼19-26 nt which suppress protein synthesis by inducing translational arrest or mRNA degradation. Here, we report a comprehensive miRNA-profiling study and show that...

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PMID: 21062812
DOI: 10.1093/nar/gkq1043

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