Constrained evolution drives limited influenza diversity

Abstract excerpt

H3N2 influenza A viruses have been widely circulating in human populations since the pandemic of 1968. A striking feature of the evolutionary development of this strain has been its 'canalized' nature, with narrow evolutionary trees dominated by long trunks with few branching, or bifurcation events and a consequent lack of standing diversity at any single point. This is puzzling, as one might expect that the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Influenza Virus Research Studies
• Share to vaccines and immunoinformatics approaches
• Share to Vibrio bacteria research studies