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Evolution of human respiratory virus epidemics

29 Jul 2021

Abstract excerpt

Background: Pathogens are often assumed to evolve towards reduced virulence, but counterexamples abound. Faced with a new pathogen, such as SARS-CoV-2, it is crucial to be able to forecast the case fatality rate (CFR) and the overall disease burden. Considerable effort has been invested towards developing a mathematical framework for predicting virulence evolution. Although many approaches accurately recapitulate...

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PMID: 34484689
DOI: 10.12688/f1000research.53392.2

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