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Article

Host immunity and pathogen diversity: A computational study.

Virulence - 1 Jan 2016

Aquino Tomás, Nunes Ana

Abstract excerpt

The distinctive features of human influenza A phylogeny have inspired many mathematical and computational studies of viral infections spreading in a host population, but our understanding of the mechanisms that shape the coupled evolution of host immunity, disease incidence and viral antigenic properties is far from complete. In this paper we explore the epidemiology and the phylogeny of a rapidly mutating...

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Identifiers

PMID: 26836775
DOI: 10.1080/21505594.2016.1149284
PMCID: PMC4994829

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