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Article

A two-tiered model for simulating the ecological and evolutionary dynamics of rapidly evolving viruses, with an application to influenza.

Journal of the Royal Society, Interface - 6 Sept 2010

Koelle Katia, Khatri Priya, Kamradt Meredith, Kepler Thomas B

Abstract excerpt

Understanding the epidemiological and evolutionary dynamics of rapidly evolving pathogens is one of the most challenging problems facing disease ecologists today. To date, many mathematical and individual-based models have provided key insights into the factors that may regulate these dynamics. However, in many of these models, abstractions have been made to the simulated sequences that limit an effective...

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Identifiers

PMID: 20335193
DOI: 10.1098/rsif.2010.0007
PMCID: PMC2894885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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