Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innate IFNs and Plasmacytoid Dendritic Cells Constrain Th2 Cytokine Responses to Rhinovirus: A Regulatory Mechanism with Relevance to Asthma

20 May 2012

Abstract excerpt

Human rhinoviruses (RV) cause only minor illness in healthy individuals, but can have deleterious consequences in people with asthma. This study sought to examine normal homeostatic mechanisms regulating adaptive immunity to RV in healthy humans, focusing on effects of IFN-αβ and plasmacytoid dendritic cells (pDC) on Th2 immune responses. PBMC were isolated from 27 healthy individuals and cultured with RV16 for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergic Rhinitis and Sensitization
Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22611238
DOI: 10.4049/jimmunol.1103507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innate IFNs and Plasmacytoid Dendritic Cells Constrain Th2 Cytokine Responses to Rhinovirus: A Regulatory Mechanism with Relevance to AsthmaPMID 22611238Read ↗

Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16Semantic proximity Read ↗

Recent advances in understanding rhinovirus immunitySemantic proximity Read ↗

Modulation of dendritic cell phenotype and function in asthmaSemantic proximity Read ↗

IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial EpitheliumSemantic proximity Read ↗

Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cellsSemantic proximity Read ↗

The rhinovirus puzzle: Linking virus and host factors to childhood asthma.Semantic proximity Read ↗

Regulation of human rhinovirus induced type I interferon-β, type III interferon-λ and pro-inflammatory cytokine gene expression in normal human bronchial epithelial cellsSemantic proximity Read ↗

Rhinovirus-induced epithelial RIG-I inflammasome activation suppresses antiviral immunity and promotes inflammatory responses in virus-induced asthma exacerbations and COVID-19Semantic proximity Read ↗

Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2Semantic proximity Read ↗

Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses.Semantic proximity Read ↗

Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances T(H)2 development.Semantic proximity Read ↗

Tollip SNP rs5743899 modulates human airway epithelial responses to rhinovirus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.