Article

Regulation of human rhinovirus induced type I interferon-β, type III interferon-λ and pro-inflammatory cytokine gene expression in normal human bronchial epithelial cells

2008-01-01

Abstract excerpt

Asthma is an economically important disease, with exacerbations causing significant morbidity and morality. Viral infections cause ~80% of asthma exacerbations; the majority of which are attributed to rhinovirus infection. How rhinovirus infection leads to an acute asthma exacerbation is incompletely understood. The up-regulation of proinflammatory cytokines/chemokines from rhinovirus infected bronchial epithelial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 85015d7e-1b32-50b8-9227-5b53b80aa6c5
DOI: 10.25560/4404

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Regulation of human rhinovirus induced type I interferon-β, type III interferon-λ and pro-inflammatory cytokine gene expression in normal human bronchial epithelial cellsDOI 10.25560/4404Read

Recent advances in understanding rhinovirus immunitySemantic proximity Read

Rhinovirus-induced epithelial RIG-I inflammasome activation suppresses antiviral immunity and promotes inflammatory responses in virus-induced asthma exacerbations and COVID-19Semantic proximity Read

Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activationSemantic proximity Read

Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infectionSemantic proximity Read

IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial EpitheliumSemantic proximity Read

Comparative Transcriptomic Analysis of Rhinovirus and Influenza Virus InfectionSemantic proximity Read

Toll-Like Receptor 3 Is Induced by and Mediates Antiviral Activity against Rhinovirus Infection of Human Bronchial Epithelial CellsSemantic proximity Read

Rhinovirus in the Pathogenesis and Clinical Course of Asthma.Semantic proximity Read

Human rhinovirus recognition in non-immune cells is mediated by<i>Toll</i>-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune responseSemantic proximity Read

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthmaSemantic proximity Read

Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to RhinovirusSemantic proximity Read

Regulation of IFN-λ1 Promoter Activity (IFN-λ1/IL-29) in Human Airway Epithelial CellsSemantic proximity Read