Article
Rare inborn errors associated with chronic hepatitis B virus infection.
Hepatology (Baltimore, Md.) - 1 Nov 2012
Zhao Qiang, Peng Liang, Huang Weijun, Li Qibin, Pei Yuanyuan, Yuan Ping, Zheng Lingyan, Zhang Yongling, Deng Jia, Zhong Cheng, Hu Bin, Ding Hongke, Fang Wei, Li Ru, Liao Qijun, Lin Chaoshuang, Deng Weiping, Yan Huijun, Hou Jinghui, Wu Qiuliang, Xu Tingting, Liu Jinsong, Hu Longbo, Peng Tao, Chen Suqing, Lai Kar N, Yuen Man-Fung, Wang Yue, Maini Mala K, Li Caixia, Li Miaoxin, Wang Jian, Zhang Xiuqing, Sham Pak-Chung, Wang Jun, Gao Zhi-Liang, Wang Yiming
Abstract excerpt
UNLABELLED: Chronic hepatitis B (CHB) is a major global health issue. The role of rare genetic variants in CHB has not been elucidated. We aimed to identify rare allelic variants predisposing to CHB. We performed exome sequencing in 50 CHB patients who had no identifiable risk factors for CHB and 40 controls who were healthy and hepatitis B surface antibody-positive, but had never received hepatitis B...
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