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Article

Prolonged Intrahepatic Cholestasis After Acute Hepatitis E Infection: A Case Series and Genetic Analysis.

Journal of viral hepatitis - 1 Apr 2026

Fraga Montserrat, Kasmi Sophie, Weber Susanne N, Liebe Roman, Sempoux Christine, Saadat Ali, Fellay Jacques, Kenngott-Kelber Silke, Zimmer Vincent, Lammert Frank, Krawczyk Marcin, Jüngst Christoph

Abstract excerpt

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis worldwide. Whereas HEV infection is typically self-limiting, rare cases of prolonged cholestasis have been reported. The underlying mechanisms remain unclear, though host genetic variation may contribute. This study aimed to investigate the role of genetic predisposition in HEV-induced prolonged cholestasis by analysing variants in genes...

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Topics

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Share to Adenosine Triphosphatases
Share to ATP Binding Cassette Transporter, Subfamily B, Member 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholestasis, Intrahepatic

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Share to Multidrug Resistance-Associated Protein 2

Share to Myosin Type V

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Source

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Identifiers

PMID: 41797682
DOI: 10.1111/jvh.70156
PMCID: PMC12969245

Genes

ATP8B1
MYO5B
ABCB11
ABCB4
ABCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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