Article
CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival.
Clinical & experimental metastasis - 1 Dec 2012
Meng Erhong, Long Beverely, Sullivan Paula, McClellan Steve, Finan Michael A, Reed Eddie, Shevde Lalita, Rocconi Rodney P
Abstract excerpt
Cancer cells with the surface marker profile CD44+/CD24- have previously been described to possess cancer stem cell-like properties. This manuscript evaluates those properties in ovarian cancer cell lines. The proportion of CD44+/CD24- cells corresponded to the clinical aggressiveness of each ovarian cancer cell line histologic subtype. CD44+/CD24- cells demonstrated enhanced progressive differentiation as well...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
