Article
The CD44+/CD24- phenotype relates to 'triple-negative' state and unfavorable prognosis in breast cancer patients.
Medical oncology (Northwood, London, England) - 1 Sept 2011
Giatromanolaki Alexandra, Sivridis Efthimios, Fiska Aliki, Koukourakis Michael I
Abstract excerpt
Breast carcinomas have been reported to contain a subpopulation of CD44+/CD24- tumor cells with stem cell-like properties. This study investigates the significance of these two molecules in connection with tumor aggression and prognosis. The phenotypic profile of 139 breast carcinomas was investigated in paraffin sections using markers previously associated with stem cell-like properties (CD44, CD24), the...
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