Article
CD44(high)CD24(low) molecular signature determines the Cancer Stem Cell and EMT phenotype in Oral Squamous Cell Carcinoma.
Stem cell research - 1 Mar 2016
Ghuwalewala Sangeeta, Ghatak Dishari, Das Pijush, Dey Sanjib, Sarkar Shreya, Alam Neyaz, Panda Chinmay K, Roychoudhury Susanta
Abstract excerpt
Almost all epithelial tumours contain cancer stem-like cells, which possess a unique property of self-renewal and differentiation. In oral cancer, several biomarkers including cell surface molecules have been exploited for the identification of this highly tumorigenic population. Implicit is the role of CD44 in defining CSCs but CD24 is not well-explored. Here we show that CD44(high)CD24(low) cells isolated from...
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