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Article

Polymorphisms of genes related to endothelial cells are associated with primary biliary cirrhosis patients of Cretan origin.

Human immunology - 1 Aug 2012

Mantaka Ai, Goulielmos G N, Koulentaki M, Tsagournis O, Voumvouraki A, Kouroumalis E A

Abstract excerpt

BACKGROUND: Primary biliary cirrhosis (PBC) is an organ specific autoimmune disease of still unidentified genetic etiology. We have shown that endothelins (ETs), produced by the liver endothelial cells are increased in PBC and may play a major pathogenetic role. AIMS: To study gene polymorphisms related to the endothelial cells (eNOS, EDN-1 genes) and, to investigate whether the previously reported association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22609442
DOI: 10.1016/j.humimm.2012.05.003

Genes

CTLA4

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