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Article

Genetic variants of endothelial nitric oxide synthase in patients with primary biliary cirrhosis: association with disease severity.

Journal of gastroenterology and hepatology - 1 Oct 2003

Selmi Carlo, Zuin Massimo, Biondi Maria Luisa, Invernizzi Pietro, Battezzati Pier Maria, Bernini Mara, Meda Francesca, Gershwin M Eric, Podda Mauro

Abstract excerpt

BACKGROUND AND AIMS: Primary biliary cirrhosis (PBC) presents a wide spectrum of clinical manifestations. In experimental models of liver cirrhosis and cholestasis it has been suggested that altered nitric oxide production is involved in liver injury and portal hypertension development. The present study investigated endothelial nitric oxide synthase (eNOS) genetic polymorphisms (894G/T, -786T/C) in patients with...

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Source

Identifiers

PMID: 12974901
DOI: 10.1046/j.1440-1746.2003.03160.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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