Article
Genetic polymorphism of apolipoprotein E in Caucasian alcoholic cirrhotics.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Nov 1994
Iron A, Richard P, Pascual De Zulueta M, Dumas F, Cassaigne A, Couzigou P
Abstract excerpt
Steatosis is the most common although inconstant hepatic lesion induced by chronic alcohol consumption. Alcoholic cirrhosis is found in only 20 to 30% of chronic alcohol misusers, which points to the influence of both environmental and genetic factors. Apolipoprotein E (apo E) presents an important polymorphism with three common alleles, epsilon 4, epsilon 3 and epsilon 2. Its modulation role on triglyceride-rich...
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