Article
Plasma levels of S100A4 in portopulmonary hypertension.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2009
Peng Tien, Zamanian Roham, Krowka Michael J, Benza Raymond L, Roberts Kari E, Taichman Darren B, Rybak Debbie, Trotter James F, Brown Robert S, Fallon Michael B, Kawut Steven M
Abstract excerpt
We previously showed that a single nucleotide polymorphism in S100A4 was associated with portopulmonary hypertension (PPHTN) in patients with advanced liver disease. We aimed to determine the association between plasma levels of S100A4 and PPHTN. We performed a case-control study of patients with advanced liver disease. Cases with PPHTN had mean pulmonary artery pressure >25 mmHg, pulmonary vascular resistance...
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