Article
Association study of the G-protein beta3 subunit C825T polymorphism with disease progression in patients with bladder cancer.
World journal of urology - 1 Sept 2005
Eisenhardt Andreas, Siffert Winfried, Rosskopf Dieter, Musch Michael, Mosters Max, Roggenbuck Ulla, Jöckel Karl-Heinz, Rübben Herbert, Lümmen Gerd
Abstract excerpt
The T-allele in the GNB3 C825T polymorphism has been associated with increased cell migration, a prerequisite for metastasis. In this study we investigated a potential association of the C825T-allele status and disease progression in patients with transitional cell carcinoma of the bladder (TCC). Genotyping of the GNB3 C825T polymorphism was performed in 389 patients with transitional cell carcinoma of the...
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