Article
G-protein beta3 subunit gene C825T polymorphism in patients with vesico-ureteric reflux.
Annales de genetique - 1 Jan 2000
Zagradisnik Boris, Bracic Katarina, Varda Natasa Marcun, Kokalj Vokac Nadja, Gregoric Alojz
Abstract excerpt
The C825T polymorphism in the GNB3 gene encoding a beta3 subunit from heterotrimeric G-proteins correlates strongly with the variation in activity of the G-proteins. It has so far been associated with a variety of medical conditions, but has not been tested for association with vesico-ureteric reflux (VUR). Primary VUR is a condition of genetic origin that appears to be inherited in an autosomal dominant mode,...
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