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Article

O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.

Cell stem cell - 6 Jul 2012

Jang Hyonchol, Kim Tae Wan, Yoon Sungho, Choi Soo-Youn, Kang Tae-Wook, Kim Seon-Young, Kwon Yoo-Wook, Cho Eun-Jung, Youn Hong-Duk

Abstract excerpt

O-linked-N-acetylglucosamine (O-GlcNAc) has emerged as a critical regulator of diverse cellular processes, but its role in embryonic stem cells (ESCs) and pluripotency has not been investigated. Here we show that O-GlcNAcylation directly regulates core components of the pluripotency network. Bloc...

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Source

Identifiers

PMID: 22608532
DOI: 10.1016/j.stem.2012.03.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22608532-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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